Biotechnology
How can we prevent future pandemics and accelerate progress in the life sciences?
COVID-19 has revealed both strengths and weaknesses in response to biological threats. On the one hand, the pandemic exposed how weak and ineffectual our public health systems are at controlling highly contagious airborne respiratory diseases. On the other hand, the urgency of the moment — combined with decades of previous investment — enabled us to deliver mRNA vaccines in less than nine months. Biotechnology contains much more low-hanging fruit that is ripe to be picked — if only we can implement the right public policies.
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            How Scientific Incentives Stalled the Fight Against Antibiotic Resistance, and How We Can Fix It        
        
            A million-peptide database could help us solve antibiotic resistance.        
        
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            The Case for Clinical Trial Abundance        
        
            A series of short papers outlining reform possibilities for America's clinical trials        
        
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            An Innovation Agenda for Addiction        
        
            We can advance the development of breakthrough medicines to reduce addiction at scale        
        
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            Securing Benchtop DNA Synthesizers        
        
            As the field of benchtop DNA synthesis evolves, it will require ongoing monitoring.        
        
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            Biosecurity in the Trump Era        
        
            We highlight five key moves the new administration could make to improve the nation's biosecurity        
        
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            The Triple Rapid Framework for Pandemic Diagnostics        
        
            Rapid reconfiguration, rapid deployment, and rapid results could help contain future outbreaks at their source        
        
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            Mapping America’s Biosurveillance        
        
            A comprehensive visual map of the entities that monitor biological threats across the U.S. federal government        
        
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            Congress Can Improve our Pandemic Preparedness        
        
            Strengthening the Federal Select Agent Program would mean better oversight of biotech laboratories        
        
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            Using PAHPA to Address Biosecurity Threats        
        
            A letter to House and Senate health committee leaders on making sure PAHPA mitigates biosecurity risks        
        
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            How Project NextGen Can Create Better Vaccines        
        
            A response to BARDA's request for information on the development of next generation medical countermeasures        
        
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            Preventing the Misuse of Breakthrough Health Research        
        
            A response to ARPA-H's request for information on ethical, legal, and social implications of technology development        
        
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            Making the CDC Modern        
        
            A response to the CDC's request for information on modernizing the agency        
        
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            Mitigating Risks from Dual-Use Research        
        
            A response to OSTP's request for information on developing a policy for research with certain pathogens        
        
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            How ARPA-H’s Use-Inspired Research Can Accelerate Progress in Health        
        
            Focusing on pandemic prevention will help the new agency achieve its ambitious goals – if it takes the right risks        
        
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            How At-Home Rapid Tests Could Help Prevent the Next Pandemic        
        
            Loosening restrictions on at-home rapid tests will mitigate future outbreaks        
        
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            How AI Can Help Prevent Biosecurity Disasters        
        
            A response to OSTP's request for information on a National Artificial Intelligence Strategy        
        
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            Indoor Air Quality Is the Next Great Public Health Challenge        
        
            Cleaner indoor air can increase productivity, improve student outcomes, and prevent pandemics        
        
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            Preparing for Pandemic Preparedness Legislation        
        
            Nine legislative ideas to improve our biosecurity response        
        
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            Preventing the Misuse of DNA Synthesis        
        
            The risk of engineered viruses increases as synthetic biology gets cheaper        
        
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            What Are the Odds H5N1 Is Worse Than COVID-19?        
        
            And what can we do to stop H5N1 from becoming a pandemic?        
        
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            How To Reuse the Operation Warp Speed Model        
        
            To replicate the success of OWS, we need to identify the specific characteristics that made it effective        
        
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            Three Reasons Congress Should Fund Biodefense        
        
            Cutting the Chemical Biological Defense Program would be penny-wise and pound-foolish        
        
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            Research Into Far-UVC Systems Can Help Us Prevent the Next Pandemic        
        
            A response to the EPA's request for information on better indoor air quality management        
        
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            Dwindling Food Reserves Are a National Security Risk        
        
            Policymakers have allowed the critical national security tool of food reserves to rust        
        
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            Food Reserves, Global Food Security, and International Stability        
        
            Incentivizing farmers to hold food reserves would protect global food security        
        
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            Why the Department of Defense Should Invest in Biosurveillance        
        
            Building integrated, layered, and pathogen-agnostic detection systems        
        
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            Weighing the Cost of the Pandemic        
        
            Knowing what we know now, how much damage did COVID-19 cause in the United States?         
        
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            Why BARDA Deserves More Funding        
        
            BARDA is uniquely positioned to defend the country against future pandemics and bioweapons        
        
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            Creating Advance Market Commitments and Prizes for Pandemic Preparedness        
        
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